CDS CPZ combined protocol

Definition of diseases treated with cpz combined protocol

cystic fibrosis

It is a progressive genetic disease, the cells that produce mucous, sweat and digestive juices fail by a defective gene, organic secretions become viscous with plug effect in ducts and passages, this seriously affects the lungs, the digestive system, reproductive system and other organs.

Today it can be stabilized with medicine by improving the lives of patients by extending life by 30 or 40 years.

Symptoms vary according to each person, many patients do not have symptoms until adulthood, these show atypical symptoms such as pancreatitis, pneumonia or infertility.

Symptoms:

• sinusitis
• thinness
• Salty sweat
• Persistent cough
• Nasal congestion
• Slow growth
• Stools with a bad smell
• Sibylline when breathing
• Intestinal obstruction
• Chronic constipation
• Male infertility
• Recurrent pneumonias
• Pancreatic insufficiency
• Malabsorption of fats
• Inflammation of the nostrils
• Decreased female fertility
• Difficulty with stress-consuming tasks

Types of cystic fibrosis:

• Pulmonary cystic fibrosis that may be mild, medium, or severe
• Pancreatic cystic fibrosis with pancreatic insufficiency
• According to mutations affecting the CFTR protein.

Cystic fibrosis cannot be cured, although if symptoms can be alleviated with different drugs, different therapies are applied to help patients lead a more normalized life.

• For the condition in the respiratory tract mucolytics, hypertonics and antibiotics are applied as required, respiratory physiotherapy is also worked on and physical exercise is controlled.
• For conditions in the digestive system enzymes in the pancreas are controlled and vitamins and insulin are prescribed.
• Protein therapy with enhancers and correctors.
• Gene therapy is at the start of a study to see its effectiveness.

There are cases in which lung transplantation can extend the life of patients affected by cystic fibrosis, if the lungs have deteriorated due to the disease, this process is long and hard but the quality of life is improved.

It is necessary to have an assessment to review the viability of the transplant, and the patient must have a strict follow-up to avoid future complications.